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Mouse FK506 Binding Protein Like Protein (FKBPL) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse FK506 Binding Protein Like Protein (FKBPL) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FKBPL in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
FK506-binding protein-like may play a role in the response to X-ray exposure and regulates the stability of the p21 protein by interacting with Hsp90 and p21. FKBPL is a potent anti-angiogenic factor that operates by targeting the CD44 pathway. In mouse models, the absence of FKBPL results in abnormal embryonic development, characterized by vascular development defects and embryonic lethality. FKBPL demonstrates significant anti-angiogenic effects in both physiological and pathological conditions by inhibiting endothelial cell migration and angiogenesis. For instance, in mouse tumor xenograft models, overexpression of FKBPL can suppress tumor angiogenesis, whereas its inhibition accelerates the angiogenic process.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Yakkundi, Anita et al. "The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway." PloS one vol. 8,2 (2013): e55075.