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Mouse Interleukin 18 Binding Protein (IL18BP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 18 Binding Protein (IL18BP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL18BP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interleukin-18-binding protein (IL-18BP) binds to IL-18, inhibiting its activity and serving as an inhibitor of the early TH1 cytokine response. In mice, the primary role of IL-18BP is to modulate immune responses and inflammatory processes by suppressing IL-18 activity. In the a7HMZ mouse model linked to colitis and colon cancer, IL-18BP expression is diminished, potentially contributing to impaired barrier function and a pro-inflammatory state. IL-18BP has also been researched for its role in assessing host immune responses in parasitic infections like Leishmania infantum, and it acts as a crucial factor in regulating immune responses within the tumor microenvironment.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Huang, Chenshen et al. "Chromatin Accessibility Regulates Gene Expression and Correlates With Tumor-Infiltrating Immune Cells in Gastric Adenocarcinoma." Frontiers in oncology vol. 10 609940. 5 Jan. 2021.