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Mouse Anti-Rat Interleukin 18 (IL18) Monoclonal Antibody

Cat. No.VD2N213

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for rat interleukin 18. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of rat interleukin 18.

Specifications

Application WB; IHC; ICC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone A19N25
Host Mouse
Target Species Rat
Species Reactivity Rat
Specificity Rat Interleukin 18
Isotype IgG2
Immunogen Recombinant protein of rat interleukin 18
Purification Purified by Protein A and Protein G
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat Interleukin 18 (IL18) is a pro-inflammatory cytokine belonging to the IL-1 superfamily. It is primarily produced by macrophages and other immune cells and plays a crucial role in regulating immune responses, including the induction of interferon-gamma (IFNg) production by T cells. IL-18 also influences B cell function by inhibiting IL-4 dependent IgE and IgG1 production while enhancing IgG2a production. This cytokine is involved in various inflammatory conditions and has been implicated in autoimmune diseases, neuroinflammation, and cancer.

Target Rat Interleukin 18
Target Synonym IGIF; IL-1g; IL1F4; IL1-F4; Interferon-Gamma-Inducing Factor; Interleukin-1 Family Member 4; Iboctadekin; Interleukin-1 Gamma
Gene ID 29197
UniProt ID P97636

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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