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Rabbit Anti-Mouse Dual Adaptor of Phosphotyrosine and 3-Phosphoinositides (DAPP1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse dual adaptor of phosphotyrosine and 3-phosphoinositides. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse dual adaptor of phosphotyrosine and 3-phosphoinositides.
Specifications
Target Information
Mouse dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1) is an adaptor protein encoded by the Dapp1 gene in Mus musculus, mapped to chromosome 11. It belongs to the phosphoinositide-binding adaptor family, featuring an N-terminal phosphotyrosine-binding domain and a C-terminal pleckstrin homology domain critical for ligand interactions. It localizes to cytoplasm and cell membrane, with tissue-specific expression in mouse spleen, thymus, macrophages and lymphocytes, with low levels in non-immune tissues. The protein mediates signal transduction linkage and membrane translocation, with conserved structural motifs for binding specificity. Mouse DAPP1 shares core functional domains with mammalian orthologs, and has distinct binding preferences differentiating it from other adaptor protein family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.