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Rabbit Anti-Rat Glycoprotein 130 (GP130) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat glycoprotein 130. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat glycoprotein 130.
Specifications
Target Information
Rat Glycoprotein 130 (GP130) is a key component of the signaling complexes for several cytokines, including interleukin-6 (IL6) and leukemia inhibitory factor (LIF). It is a transmembrane protein expressed on various cell types and acts as a shared receptor subunit for the IL-6 family of cytokines. Gp130 mediates signaling through the JAK-STAT pathway, regulating cell proliferation, differentiation, and survival. This protein is essential for maintaining tissue homeostasis and immune responses in rats.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Nogueira-Silva, Cristina, et al. "The role of glycoprotein 130 family of cytokines in fetal rat lung development." PLoS One 8.6 (2013): e67607.