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Canine Indoxyl Sulfate (IS) ELISA Kit-Competitive
Product Overview
BioVenic Canine Indoxyl Sulfate (IS) ELISA Kit-Competitive is designed for the quantitative determination of Canine IS in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
Canine Indoxyl Sulfate is a protein-bound uremic toxin produced from the hepatic metabolism of indole, which is generated by tryptophan-degrading bacteria in the dog's gastrointestinal tract. In canine medicine, IS is a key biomarker for renal dysfunction; its accumulation correlates with the progression of glomerular filtration rate (GFR) decline. It acts via the Aryl Hydrocarbon Receptor (AhR) to induce oxidative stress and myofibroblast transformation, making it a target for studying renal fibrosis and uremic syndrome in companion animals.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.