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Bovine Norrin (NDP) ELISA Kit-Sandwich

Name: Bovine Norrin (NDP) ELISA Kit-Sandwich
SKU: EK12F177
Rating: 5 (1 reviews)

Cat. No.EK12F177

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Norrin (NDP) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Norrin (NDP) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine NDP.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Norrin, also known as Norrie disease protein or X-linked exudative vitreoretinopathy 2 protein (EVR2), is a protein encoded by the NDP gene in cattle. Signaling induced by Norrin regulates vascular development of the vertebrate retina. It controls important blood vessels in the ear. Research has shown that norrin restores tight junction complex organization and blood-retinal barrier properties in a β-catenin-dependent manner.

Target/Biomarker Bovine NDP

Target Synonym norrin cystine knot growth factor NDP; norrin; NDP, norrin cystine knot growth factor; Norrie disease (pseudoglioma); norrie disease protein homolog

Gene ID 511596

UniProt ID Q2KI78

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Díaz-Coránguez, M. et al. Norrin restores blood-retinal barrier properties after vascular endothelial growth factor-induced permeability. The Journal of biological chemistry. 2020, 295: 4647-4660.