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Recombinant Rabbit Oxidized Low-Density Lipoprotein Receptor 1 (OLR1), N-His
Product Overview
BioVenic's Recombinant Rabbit Oxidized Low-Density Lipoprotein Receptor 1 (OLR1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.0 kDa. The purity is> 97%.
Specifications
Target Information
Rabbit Oxidized Low-Density Lipoprotein Receptor 1 (OLR1) is a key receptor involved in lipid metabolism and immune responses. It is primarily expressed in endothelial cells and macrophages, where it binds and internalizes oxidized low-density lipoprotein (ox-LDL), contributing to the development of atherosclerosis. In rabbits, OLR1 is also implicated in hypertension-induced neuronal apoptosis and may play a role in brain damage following stroke. Additionally, OLR1 has been shown to mediate inflammatory responses and oxidative stress, which are critical in various cardiovascular and cerebrovascular diseases. Its expression can serve as a biomarker for these conditions and may be a potential therapeutic target for interventions aimed at reducing inflammation and preventing tissue damage.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.