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Recombinant Mouse Interleukin-34 (Il34), N-His
Product Overview
BioVenic's Recombinant Mouse Interleukin-34 (Il34), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 26.1 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Interleukin-34 (Il34) is a cytokine that plays a significant role in immune regulation and neuroprotection. It acts as a ligand for the colony-stimulating factor-1 receptor (CSF-1R) and is essential for the development and function of microglia, the resident immune cells of the central nervous system. In mouse models, Il34 has been shown to promote microglial proliferation and support their neuroprotective functions. For instance, in the APP/PS1 mouse model of Alzheimer's disease, Il34 administration improved cognitive function by modulating microglial activity.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.