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Recombinant Mouse Interleukin-33 (Il33), N-GST
Product Overview
BioVenic's Recombinant Mouse Interleukin-33 (Il33), N-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 43.1 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Interleukin-33 (Il33) is a cytokine belonging to the IL-1 family, primarily acting as an alarmin that alerts the immune system to tissue damage. It is expressed in various tissues, including the lung, brain, and gut, and is highly abundant in endothelial cells and epithelial cells. Il33 signals through its receptor complex composed of ST2 and IL-1RAP, activating the NF-κB and MAPK signaling pathways. This cytokine induces Th2-associated cytokines such as IL-4, IL-5, and IL-13, promoting allergic inflammation and host defense against microbial and viral infections.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.