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Recombinant Feline Interleukin-10 (IL10)
Product Overview
BioVenic's Recombinant Feline Interleukin-10 (IL10) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.9 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Feline interleukin-10 (IL10) is a key immune regulator that mitigates inflammation by binding to its receptor (IL10RA/IL10RB), activating JAK1 and STAT2, leading to STAT3-mediated anti-inflammatory gene expression. IL10 targets antigen-presenting cells (APCs), reducing pro-inflammatory cytokines and hindering antigen presentation. It is crucial for controlling macrophage inflammation through metabolic reprogramming and plays a significant role in immune homeostasis and the regulation of both innate and adaptive immunity.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.Aliquote the reconstituted solution to minimise freeze-thaw cycles.