Recombinant Mouse Clusterin (Clu), N-His

Mouse Clusterin (Clu) is a multifunctional protein involved in various biological processes, including cell apoptosis, lipid transport, and tissue repair. It is expressed in multiple tissues and is secreted into bodily fluids. Clu plays a role in the clearance of cellular debris and misfolded proteins, contributing to cellular homeostasis. In the context of apoptosis, Clu can either promote or inhibit cell death, depending on the cellular context and stress conditions. It is also involved in lipid metabolism, interacting with lipoproteins and facilitating lipid transport. Research suggests that Clu may protect against oxidative stress and inflammation. Its expression is elevated in certain diseases, including neurodegenerative disorders and cancer, where it may contribute to disease progression or serve as a biomarker. Understanding the diverse functions of Clu could provide insights into its roles in health and disease.