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Recombinant Bovine Insulin-like Growth Factor-Binding Protein 1 (IGFBP1)
Product Overview
BioVenic's Recombinant Bovine Insulin-like Growth Factor-Binding Protein 1 (IGFBP1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.3 kDa. The purity is> 97%.
Specifications
Target Information
Bovine Insulin-like Growth Factor-Binding Protein 1 (IGFBP1) is a key protein involved in regulating uterine receptivity and conceptus elongation in cattle. IGFBP1 is highly expressed in the endometrial epithelium during early pregnancy and serves as a marker for uterine receptivity. It is regulated by various factors, including tryptophan and its metabolite kynurenine, which enhance IGFBP1 expression via the PGE2-TDO2-AHR signaling pathway. This regulation is crucial for successful embryo implantation and pregnancy maintenance. IGFBP1 also plays a role in modulating the uterine environment to support conceptus development and growth.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.