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Recombinant Chicken Integrin Alpha-V (ITGAV)
Product Overview
BioVenic's Recombinant Chicken Integrin Alpha-V (ITGAV) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 114.4 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Integrin Alpha-V (ITGAV) is a critical component of the integrin family, playing a significant role in cell adhesion, migration, and signaling. ITGAV forms heterodimers with various beta subunits (such as β1, β3, β5, β6, and β8) to mediate interactions between cells and the extracellular matrix (ECM). This integrin is particularly important in processes such as angiogenesis, tissue repair, and immune response. In chickens, ITGAV is highly expressed in tissues involved in these processes and is essential for maintaining cellular integrity and function. Abnormal expression of ITGAV has been implicated in various diseases, including cancer, where it can promote tumor progression and metastasis through the activation of downstream signaling pathways.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.