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Recombinant Mouse Nicotinamide Phosphoribosyltransferase (Nampt), N-His
Product Overview
BioVenic's Recombinant Mouse Nicotinamide Phosphoribosyltransferase (Nampt), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 59.1 kDa. The purity is> 80%.
Specifications
Target Information
Mouse Nicotinamide Phosphoribosyltransferase (Nampt) is a key enzyme in the NAD+ salvage pathway, catalyzing the conversion of nicotinamide to nicotinamide mononucleotide (NMN), which is essential for NAD+ synthesis. NAD+ is crucial for energy metabolism, DNA repair, and cell signaling. Nampt exists in both intracellular (iNampt) and extracellular (eNampt) forms. iNampt is highly expressed in tissues like brown adipose tissue, liver, and kidneys, while eNampt is secreted primarily from adipose tissue and acts as a cytokine, influencing metabolism and inflammation.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.