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Recombinant Canine C-C Motif Chemokine 4 (CCL4)
Product Overview
BioVenic's Recombinant Canine C-C Motif Chemokine 4 (CCL4) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 7.8 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine C-C motif chemokine 4 (CCL4), also known as macrophage inflammatory protein-1 beta (MIP-1β), is a CC chemokine that specifically binds to CCR5 receptors and plays a role in chemoattracting natural killer cells, monocytes, and other immune cells. It is involved in processes such as negative regulation of viral transcription, positive regulation of calcium-mediated signaling, and natural killer cell chemotaxis. In dogs, CCL4 is implicated in the immune response and may be a biomarker for diseases like autoimmune disorders and certain infections.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstituteat 100 μg/mL in 4 mM HCl containing at least 0.3% human or bovine serum albumin.Aliquote the reconstituted solution to minimise freeze-thaw cycles.