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Rabbit Anti-Sheep Superoxide Dismutase 1 (SOD1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for sheep superoxide dismutase 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of sheep superoxide dismutase 1.
Specifications
Target Information
Sheep superoxide dismutase 1 (SOD1) is a 16 kDa cytosolic Cu/Zn homodimer whose Greek-key β-barrel and electrostatic loop guide superoxide to the active-site metal, converting O₂⁻ to H₂O₂. A solvent-exposed 14-aa "KVE" loop (aa 57-70) between β-strands 4 and 5 folds into a β-hairpin unique among sheep SOD isoforms, presenting a conformational epitope preserved after metal chelation and fixation. Affinity-purified antibodies targeting this loop trace native SOD1 in spinal cord motor neurons, hepatic cytosol, and erythrocytes, delivering crisp cytoplasmic puncta and single-band clarity on immunoblots with no cross-reaction to SOD2 or SOD3.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.