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Rabbit Anti-Reverse Triiodothyronine (rT3) Polyclonal Antibody

Cat. No.VD4N308

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for reverse triiodothyronine. It is purified by protein A/G. It can be applied to ELISA, CLIA/IHC-Fr and ICC assays of reverse triiodothyronine.

Specifications

Application ELISA; CLIA/IHC-Fr; ICC
Clonality Polyclonal
Classification Primary Antibody
Clone C3N380
Host Rabbit
Target Species General
Species Reactivity General
Specificity Reverse Triiodothyronine
Isotype IgG
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.47 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Reverse triiodothyronine (rT3) is a 651-Da thyroid metabolite whose 3,3',5'-triiodo configuration blocks thyroid-hormone receptors, acting as a natural T3 antagonist. A solvent-exposed 5-aa "KVE" hapten (3,3',5'-triiodothyronine) linked to carrier proteins presents a fixation-stable epitope unique among thyroid hormone analogs. Antibodies to this conjugate detect rT3 in serum, hepatic cytosol and placental extracts, yielding crisp intracellular staining and single-band blots without cross-reaction to T3 or T4.

Target Reverse Triiodothyronine
Target Synonym RT3; r-T3; Reverse T3; (2S)-2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3-Iodophenyl]propanoic Acid; 3,3',5'-Triiodo-L-thyronine

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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