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Rabbit Anti-Mouse Myosin IA (MYO1A) Polyclonal Antibody

Cat. No.VD1N86

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse myosin IA. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse myosin IA.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A2N28
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Myosin IA
Isotype IgG
Immunogen Recombinant protein of mouse myosin IA
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse Myosin IA (MYO1A) is an unconventional class I myosin motor protein that plays a crucial role in the structure and function of the intestinal brush border. It is predominantly expressed in enterocytes, where it links the apical membrane to the underlying actin bundles through its C-terminal tail domain. MYO1A is essential for maintaining the structural integrity of microvilli and for the movement of the apical membrane along actin filaments, leading to the release of vesicles from microvillar tips. Additionally, it contributes to membrane-cytoskeleton adhesion, enabling the apical membrane to resist deformation.

Target Mouse Myosin IA
Target Synonym MYO1-A; MIHC; BBMI; DFNA48; MYHL; Brush border myosin I; Myosin I heavy chain
Gene ID 432516
UniProt ID O88329

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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