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Rabbit Anti-Rat Synuclein Alpha (SNCa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat synuclein alpha. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat synuclein alpha.
Specifications
Target Information
Rat α-Synuclein is a member of the synuclein family, abundantly expressed in the brain. It plays key roles in synaptic activity, including regulation of synaptic vesicle trafficking and neurotransmitter release. As a monomer, it enhances vesicle priming and fusion, crucial for synaptic function. In its multimeric state, α-Synuclein acts as a molecular chaperone, assisting in the folding of SNARE proteins at the presynaptic membrane. It is also involved in dopamine neurotransmission by interacting with the dopamine transporter (DAT1). Abnormal aggregation of α-Synuclein is associated with neurodegenerative diseases such as Parkinson's disease and Lewy body dementia.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.