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Rabbit Anti-Mouse Transition Protein 1 (TNP1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse transition protein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse transition protein 1.
Specifications
Target Information
Mouse transition protein 1 (TNP1) is a 54-residue, arginine- and cysteine-rich chromatin condensing factor expressed exclusively in post-meiotic round spermatids. The peptide replaces histones transiently between histone removal and protamine deposition, using its numerous positively charged residues to neutralize DNA phosphate groups while intra- and inter-molecular disulfide bonds stabilize the condensed fiber. The protein is synthesized as a 6.2 kDa precursor that undergoes proteolytic trimming of a short N-terminal leader during epididymal transit. Antibodies raised against full-length recombinant mouse TNP1 recognize both the precursor and processed forms with negligible cross-reactivity to protamines or transition protein 2, enabling specific immunoblot and immunohistochemical detection in testicular homogenates and epididymal sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.