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Rabbit Anti-Mouse Interleukin 1 Receptor Type I (IL1R1) Polyclonal Antibody

Cat. No.VD1N271

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse interleukin 1 receptor type I. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 1 receptor type I.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A6N21
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Interleukin 1 Receptor Type I
Isotype IgG
Immunogen Recombinant protein of mouse interleukin 1 receptor type I
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse Interleukin 1 Receptor Type I (IL1R1) is a transmembrane protein essential for mediating interleukin-1 (IL1) signaling. It is widely expressed in various cell types and plays a crucial role in initiating inflammatory responses. IL-1R1 binds to IL-1α and IL-1β, activating intracellular signaling pathways such as NF-κB and MAPK, which lead to the production of pro-inflammatory cytokines and the regulation of immune responses. This receptor is a key component of the innate immune system and is critical for host defense against pathogens.

Target Mouse Interleukin 1 Receptor Type I
Target Synonym CD121a; CD121-A; IL1-R1; IL1R; IL1RA; P80; CD121 Antigen-Like Family Member A; Interleukin-1 Receptor Alpha
Gene ID 16177
UniProt ID P13504

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Slack, Jennifer, et al. "Independent binding of interleukin-1 alpha and interleukin-1 beta to type I and type II interleukin-1 receptors." Journal of Biological Chemistry 268.4 (1993): 2513-2524.
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