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Rabbit Anti-Mouse Interleukin 1 Receptor Type I (IL1R1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 1 receptor type I. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 1 receptor type I.
Specifications
Target Information
Mouse Interleukin 1 Receptor Type I (IL1R1) is a transmembrane protein essential for mediating interleukin-1 (IL1) signaling. It is widely expressed in various cell types and plays a crucial role in initiating inflammatory responses. IL-1R1 binds to IL-1α and IL-1β, activating intracellular signaling pathways such as NF-κB and MAPK, which lead to the production of pro-inflammatory cytokines and the regulation of immune responses. This receptor is a key component of the innate immune system and is critical for host defense against pathogens.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Slack, Jennifer, et al. "Independent binding of interleukin-1 alpha and interleukin-1 beta to type I and type II interleukin-1 receptors." Journal of Biological Chemistry 268.4 (1993): 2513-2524.