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Rabbit Anti-Mouse Diacylglycerol Kinase Gamma (DGKg) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse diacylglycerol kinase gamma. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse diacylglycerol kinase gamma.
Specifications
Target Information
Mouse diacylglycerol kinase gamma (DGKγ) is a 70 kDa membrane-associated kinase whose N-terminal EF-hands, C1 domains and C-terminal catalytic pocket convert DAG to phosphatidic acid, using ATP to terminate lipid signaling. A solvent-exposed 16-aa "KVE" loop (aa 420-435) between the kinase core and the MARCKS-homology region folds into a β-hairpin unique among mouse DGK isoforms, presenting a conformational epitope preserved after membrane binding and fixation. Affinity-purified antibodies targeting this loop trace native DGKγ in cortical synapses, hippocampal dendrites, and cardiac sarcolemma, delivering crisp punctate membranes and single-band clarity on immunoblots with no cross-reaction to DGKα or DGKζ.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.