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Rabbit Anti-Mouse Aminoadipate Semialdehyde Synthase (AASS) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse aminoadipate semialdehyde synthase. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse aminoadipate semialdehyde synthase.
Specifications
Target Information
Mouse aminoadipate semialdehyde synthase (AASS) is a bifunctional cytosolic enzyme with two conserved catalytic domains, a core component of lysine catabolism pathways. It features an N-terminal lysine-ketoglutarate reductase domain and a C-terminal saccharopine dehydrogenase domain, both critical for sequential catalytic reactions. It localizes predominantly to the cytoplasm of mouse hepatocytes and renal cells, with negligible expression in skeletal muscle and nervous tissues. The protein mediates the initial two steps of lysine degradation via domain-specific substrate binding, with conserved structural motifs differentiating it from single-domain metabolic enzymes.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.