Get a quote

We're excited to learn more about your project and provide you with a customized quote tailored to your needs. Please fill out the form below, and we'll get back to you as soon as possible.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Rabbit Anti-Mouse Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Polyclonal Antibody

Cat. No.VD2N877

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse eukaryotic translation initiation factor 4E binding protein 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse eukaryotic translation initiation factor 4E binding protein 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N376
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Isotype IgG
Immunogen Recombinant protein of mouse eukaryotic translation initiation factor 4E binding protein 1
Purification Protein A Purified
Concentration 0.39 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (4E-BP1) is a key regulator of protein synthesis. It binds to eIF4E, inhibiting its ability to initiate translation, thereby controlling the expression of specific mRNAs. 4E-BP1 is phosphorylated by mTOR, leading to its inactivation and allowing translation to proceed. This protein plays a crucial role in cellular growth, proliferation, and stress responses by modulating translation initiation. As a central component of the mTOR signaling pathway, 4E-BP1 is an important target for studying cellular metabolism, growth regulation, and potential therapeutic interventions related to cancer and metabolic disorders.

Target Mouse Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Target Synonym 4EBP1; BP-1; PHAS-I; Phosphorylated Heat and Acid-Stable Protein Regulated By Insulin 1
Gene ID 13685
UniProt ID P63073

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

Inquiry Basket