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Mouse Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DVL1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Segment polarity protein dishevelled homolog DVL-1 is involved in Wnt signaling by interacting with the cytoplasmic C-terminus of frizzled family members, transmitting the Wnt signal to downstream effectors. It functions in both canonical and non-canonical Wnt pathways. In mice, the lack of Dvl1 results in defects in synaptic assembly. For instance, mice with both Wnt7a and Dvl1 mutations exhibit reduced presynaptic protein accumulation, leading to impaired synaptic transmission. These mice particularly show a marked reduction in the frequency of presynaptic currents (mEPSCs) at vagal fiber-granule cell synapses in the cerebellum, while the amplitude remains unaffected.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.