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Mouse Podoplanin (PDPN) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Podoplanin (PDPN) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PDPN in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Podoplanin influences cell migration and adhesion through interactions with various partners. During development, it plays a crucial role in the separation of blood and lymphatic vessels by binding to CLEC1B, activating platelets, and leading to platelet activation and/or aggregation. Podoplanin is essential for lymphatic vessel development, particularly in lymphocyte and endothelial cell differentiation. It promotes the separation of blood and lymph by binding to C-type lectin-like receptor 2 (CLEC-2), thereby maintaining the integrity of the lymphatic system. Mice lacking Podoplanin exhibit abnormal lymphatic vessel development, resulting in irregular lymph node formation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Astarita, Jillian L et al. "Podoplanin: emerging functions in development, the immune system, and cancer." Frontiers in immunology vol. 3 283. 12 Sep. 2012.