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Diphtheria Toxin-BSA Antigen
Product Overview
BioVenic's Diphtheria Toxin-BSA Antigen is a conjugated antigen prepared using chemical coupling. It can be used in immunochromatographic platforms like colloidal gold/fluorescence, the development of ELISA assays, and for immunizing animals to produce antibodies.
Specifications
Target Information
Diphtheria toxin is an extremely potent exotoxin secreted by the bacterium Corynebacterium diphtheriae, and occasionally by Corynebacterium ulcerans. In veterinary medicine and food safety, C. ulcerans can infect livestock, particularly dairy cows, causing mastitis. The toxin can then be shed directly into raw milk. Diphtheria toxin inhibits eukaryotic protein synthesis by catalyzing the ADP-ribosylation of elongation factor 2 (EF-2), leading to cellular death. Ingestion of unpasteurized milk contaminated with this toxin or the toxigenic bacteria poses a severe public health risk, potentially causing diphtheria-like symptoms, upper respiratory tract lesions, and systemic complications like myocarditis or polyneuritis in humans.
Shipping and Storage
This product is shipped with ice packs. Stored at -20°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Aliquot the reconstituted solution to minimize freeze-thaw cycles.