Recombinant Mouse Transcription Factor p65 (Rela), N-His

Mouse Transcription Factor p65 (Rela) is a key subunit of the NF-κB family of transcription factors, which plays a central role in regulating immune and inflammatory responses, cell proliferation, survival, and migration. It is activated in response to various stimuli, including infection, inflammation, and genotoxic stress. p65 binds to DNA and induces the expression of numerous genes involved in immune responses, apoptosis, and stress adaptation. It also interacts with other transcription factors and epigenetic regulators to modulate gene expression networks. Additionally, p65 undergoes post-translational modifications such as phosphorylation and acetylation, which regulate its DNA-binding activity and transcriptional functions. In mouse models, p65 is implicated in diseases like cancer and autoimmune disorders, making it a potential therapeutic target.