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Recombinant Canine Cholinesterase (BCHE), N-His

Cat. No.AP9C581

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Cholinesterase (BCHE), N-His is a recombinant protein expressed from Yeast. Its predicted molecular weight is 17.1 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System Yeast
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 17.1 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Target Information

Canine cholinesterase (BCHE) is a crucial enzyme in dogs that plays a significant role in the hydrolysis of esters, including the breakdown of neurotransmitters such as acetylcholine and butyrylcholine. It is involved in the regulation of synaptic transmission and has been implicated in the detoxification of certain poisons and drugs. Recent studies have highlighted its potential therapeutic use in treating canine cognitive dysfunction, where it can help improve cognitive abilities and reduce the symptoms of age-related cognitive decline.

Protein Canine Cholinesterase (BCHE)
Protein Synonym Acylcholine acylhydrolase;
Butyrylcholine esterase;
Choline esterase II;
Pseudocholinesterase;
Gene ID 488143
UniProt ID P32750

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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