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Rabbit Anti-Rat Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Polyclonal Antibody

Cat. No.VD4N561

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat triggering receptor expressed on myeloid cells 2. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat triggering receptor expressed on myeloid cells 2.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C4N194
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Triggering Receptor Expressed on Myeloid Cells 2
Isotype IgG
Immunogen Recombinant protein of rat triggering receptor expressed on myeloid cells 2
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.8 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane glycoprotein of the TREM family. It features a conserved extracellular immunoglobulin-like domain, a single transmembrane segment and a short cytoplasmic tail critical for structural integrity. It localizes to cell membranes of rat microglia, macrophages and osteoclasts, with negligible levels in non-myeloid tissues. The protein mediates cell activation and signal transduction, with conserved motifs for ligand binding and adapter protein interaction. Rat TREM2 shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from TREM1.

Target Rat Triggering Receptor Expressed on Myeloid Cells 2
Target Synonym Trem2a; Trem2b; Trem2c; Triggering receptor expressed on monocytes 2;
Gene ID 301227
UniProt ID A0A6G8MV71

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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