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Rabbit Anti-Rat Osteopontin (OPN) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat osteopontin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat osteopontin.
Specifications
Target Information
Rat osteopontin (OPN) is a secreted phosphorylated glycoprotein of the SIBLING family, a multifunctional mediator of cell adhesion and tissue remodeling. It features a conserved N-terminal signal peptide, a central RGD integrin-binding motif, and a C-terminal calcium-binding region critical for structural integrity and ligand interaction. It localizes to the extracellular matrices of rat bone, kidney and immune tissues, with negligible levels in skeletal muscle and nervous tissues. The protein mediates cell migration and inflammatory response modulation, with conserved motifs for binding to integrins and CD44. Rat OPN shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from bone sialoprotein and dentin matrix protein 1.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.