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Rabbit Anti-Rat Orexin A (OXA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat orexin A. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat orexin A.
Specifications
Target Information
Rat orexin A is a 33-amino-acid, C-terminally amidated neuropeptide excised from the 130-residue prepro-orexin precursor by prohormone convertases. The peptide contains four cysteines that form two intramolecular disulfide bridges (Cys6-Cys12, Cys7-Cys14), generating a compact cyclic structure essential for receptor binding. Expressed selectively in lateral and posterior hypothalamic neurons, orexin A is packaged in dense-core vesicles and released along axonal projections to thalamic and brainstem targets. Antibodies raised against the full cyclic peptide or C-terminal fragments detect native orexin A with negligible cross-reactivity to orexin B or other hypothalamic peptides, enabling precise immunohistochemical and immunoblot visualization in rat brain extracts and tissue sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.