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Rabbit Anti-Rat Metallothionein 1 (MT1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat metallothionein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat metallothionein 1.
Specifications
Target Information
Rat metallothionein 1 (MT-1) is a 61-residue, cysteine-rich (20 Cys) protein that folds into two metal-thiolate clusters binding up to seven zinc or cadmium ions. The polypeptide lacks aromatic amino acids and adopts a dumbbell structure with separate four- and three-metal domains connected by a conserved Lys-Lys hinge. Constitutively expressed in liver, kidney and duodenum, MT-1 localizes to cytosol and nucleus, buffering intracellular zinc and scavenging free radicals. Antibodies raised against recombinant rat MT-1 detect native, metal-bound and apo-forms with negligible cross-reactivity to MT-2 or MT-3, enabling selective immunoblot and immunohistochemical visualization in rat tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.