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Rabbit Anti-Rat Lipopolysaccharide Binding Protein (LBP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat lipopolysaccharide binding protein. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat lipopolysaccharide binding protein.
Specifications
Target Information
Rat lipopolysaccharide binding protein (LBP) is a secreted acute-phase glycoprotein of the BPI/LBP family, a core mediator of Gram-negative bacterial immune recognition. It features a conserved N-terminal LPS-binding domain, a C-terminal lipid transfer domain, and structural motifs critical for ligand interaction and protein stability. It localizes to rat plasma and extracellular fluids, with high expression in hepatocytes and negligible levels in non-hepatic tissues. The protein mediates LPS transfer to CD14 and TLR4/MD-2 complex, with conserved motifs for binding to bacterial lipopolysaccharides. Rat LBP shares core functional domains with mammalian orthologs, and has distinct binding affinity differentiating it from bactericidal/permeability-increasing protein (BPI).
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.