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Rabbit Anti-Rat High Mobility Group Protein 1 (HMGB1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat high mobility group protein 1. It is affinity purified by protein A. It can be applied to WB and IHC assays of rat high mobility group protein 1.
Specifications
Target Information
Rat high mobility group protein 1 (HMGB1) is a multifunctional protein with essential roles in both nuclear and extracellular environments. Within the nucleus, HMGB1 binds to DNA and assists in chromatin remodeling, transcription regulation, and DNA repair. When released extracellularly, it acts as a damage-associated molecular pattern (DAMP) molecule, triggering immune responses and promoting inflammation. HMGB1 is widely expressed in various tissues and is involved in processes such as cell differentiation, apoptosis, and tissue repair. As a key player in both cellular homeostasis and immune signaling, HMGB1 is an important target for studying inflammatory diseases and tissue injury.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.