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Rabbit Anti-Rat Complement Factor B (CFB) Polyclonal Antibody

Name: Rabbit Anti-Rat Complement Factor B (CFB) Polyclonal Antibody
SKU: VD3N205
Rating: 5 (1 reviews)

Cat. No.VD3N205

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for rat complement factor B. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat complement factor B.

Specifications

Application WB; IHC; ICC; IP

Clonality Polyclonal

Classification Primary Antibody

Clone Y1N703

Host Rabbit

Target Species Rat

Species Reactivity Rat

Specificity Rat Complement Factor B

Isotype IgG

Immunogen Recombinant protein of rat complement factor B

Purification Protein A Purified

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol

Physical State Liquid

Target Information

Rat Complement Factor B (CFB) is a key component of the alternative pathway of the complement system. It is involved in the activation of the complement cascade, leading to the formation of the C3 convertase and subsequent immune responses. CFB is synthesized in the liver and is essential for maintaining immune homeostasis and protecting against infections. As a central regulator of the complement system, CFB is an important target for studying immune defense mechanisms and potential therapeutic interventions in complement-related disorders.

Target Rat Complement Factor B

Target Synonym CF-B; BF; BFD; CFAB; GBG; H2-Bf; PBF2; B-Factor; Properdin; Properdin factor B; C3/C5 convertase; Glycine-rich beta glycoprotein

Gene ID 294257

UniProt ID Q6MG74

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Jager, Neeltina M., et al. "Blocking complement factor B activation reduces renal injury and inflammation in a rat brain death model." Frontiers in immunology 10 (2019): 2528.