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Mouse Anti-Rat Nephrin (NPHN) Monoclonal Antibody

Cat. No.VD2N251

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for rat nephrin. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of rat nephrin.

Specifications

Application WB; IHC; ICC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone A22N22
Host Mouse
Target Species Rat
Species Reactivity Rat
Specificity Rat Nephrin
Isotype IgG2
Immunogen Recombinant protein of rat nephrin
Purification Purified by Protein A and Protein G
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat nephrin is a key protein component of the glomerular filtration barrier in the kidney. It is expressed in podocytes, where it forms a crucial part of the slit diaphragm, a structure essential for maintaining the selective permeability of the glomerular filter. Nephrin plays a vital role in preventing proteinuria by ensuring proper filtration function. Its expression and integrity are critical for normal kidney function, and disruptions in nephrin can lead to proteinuria and kidney disease.

Target Rat Nephrin
Target Synonym NPHS1; CNF; Nephrosis 1; Congenital Finnish Type; Renal glomerulus-specific cell adhesion receptor
Gene ID 64563
UniProt ID Q9R044

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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