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Rabbit Anti-Rat Complement Component 7 (C7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat complement component 7. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat complement component 7.
Specifications
Target Information
Rat complement component 7 (C7) is a secreted glycoprotein encoded by the C7 gene in Rattus norvegicus, mapped to chromosome 3. It belongs to the complement component family, featuring conserved complement control protein domains, a membrane attack complex perforin-like region and multiple cysteine-rich motifs critical for function. It localizes to systemic circulation and interstitial fluid, with ubiquitous expression in rat tissues and consistent secretion by hepatocytes. The protein is a core component for membrane attack complex assembly, with conserved structural sites for binding to other complement components. Rat C7 shares core functional domains with mammalian orthologs, and has distinct interaction specificity differentiating it from C5, C6 and other terminal complement components.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.