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Rabbit Anti-Mouse Phosphofructokinase (PFKP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse phosphofructokinase, platelet. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse phosphofructokinase, platelet.
Specifications
Target Information
Mouse phosphofructokinase, platelet isoform (PFKP) is a 784-residue cytosolic tetramer that catalyzes the ATP-dependent phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Its N-terminal catalytic domain contains the conserved 244-Gly-Gly-Ala-Ser-Asn-248 motif, while a C-terminal regulatory region binds ATP, citrate and ADP to control glycolytic flux. Constitutively expressed in megakaryocytes, spleen and brain, PFKP localizes to cytoplasm and cytoskeletal junctions. Antibodies raised against the catalytic or regulatory peptide detect native, phosphorylated and acetylated forms with negligible cross-reactivity to liver or muscle PFK isoforms, enabling selective immunoblot and immunofluorescence visualization in mouse tissue homogenates and cultured cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.