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Rabbit Anti-Rat Semaphorin 4D (SEMA4D) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat semaphorin 4D. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat semaphorin 4D.
Specifications
Target Information
Rat semaphorin 4D (SEMA4D) is a transmembrane glycoprotein encoded by the Sema4d gene in Rattus norvegicus, mapped to chromosome 12. It belongs to the class IV semaphorin family, featuring a conserved N-terminal SEMA domain, a plexin-semaphorin-integrin domain, a transmembrane segment and a short cytoplasmic tail. It localizes to cell membrane, with tissue-specific expression in rat immune cells, neurons, endothelial and epithelial cells, with low levels in muscle tissues. The protein mediates cell guidance and intercellular interaction, with conserved motifs for ligand-receptor binding and structural stability. Rat SEMA4D shares core functional domains with mammalian orthologs, and has distinct binding specificity differentiating it from SEMA4A and other semaphorin family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.