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Rabbit Anti-Mouse Macrophage Expressed Gene 1 Protein (MPG1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse macrophage expressed gene 1 protein. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse macrophage expressed gene 1 protein.
Specifications
Target Information
Mouse macrophage expressed gene 1 protein (MPEG1) is a transmembrane protein encoded by the Mpeg1 gene in Mus musculus, mapped to chromosome 17. It belongs to the perforin-like protein family, featuring a conserved N-terminal pore-forming domain, multiple glycine-rich repeats and a C-terminal transmembrane region. It localizes to cell membrane and lysosomal compartments, with tissue-specific expression in mouse macrophages, microglia and other myeloid lineage cells, with negligible levels in non-immune tissues. The protein mediates membrane interaction and intracellular vesicle trafficking, with conserved motifs critical for structural integrity and oligomerization. Mouse MPEG1 shares core functional domains with mammalian orthologs, and has distinct cell-type distribution differentiating it from other perforin-like family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.