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Rabbit Anti-Mouse Caspase 9 (CASP9) Polyclonal Antibody

Name: Rabbit Anti-Mouse Caspase 9 (CASP9) Polyclonal Antibody
SKU: VD2N53
Rating: 5 (1 reviews)

Cat. No.VD2N53

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse caspase 9. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse caspase 9.

Specifications

Application WB; IHC; ICC; IP

Clonality Polyclonal

Classification Primary Antibody

Clone A13N31

Host Rabbit

Target Species Mouse

Species Reactivity Mouse

Specificity Mouse Caspase 9

Isotype IgG

Immunogen Recombinant protein of mouse caspase 9

Purification Protein A Purified

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.05% Proclin 300

Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol

Physical State Liquid

Target Information

Mouse Caspase 9 is a key enzyme in the intrinsic apoptotic pathway. It is activated in response to cellular stress and mitochondrial signals, leading to the cleavage of downstream caspases and the initiation of apoptosis. Caspase 9 forms part of the apoptosome complex, which is crucial for executing programmed cell death. This enzyme plays a critical role in maintaining cellular homeostasis by regulating apoptosis in response to DNA damage and other stressors.

Target Mouse Caspase 9

Target Synonym APAF3; ICE-LAP6; MCH6; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 9; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6

Gene ID 12371

UniProt ID Q8C3Q9

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Nakanishi, Keiko, et al. "Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development." Journal of Biological Chemistry 276.44 (2001): 41237-41244.