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Rabbit Anti-Mouse Intestinal Cell Kinase (ICK) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse intestinal cell kinase. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse intestinal cell kinase.
Specifications
Target Information
Mouse intestinal cell kinase (ICK) is a serine/threonine kinase of the CDC2-like kinase family, a core regulator of intestinal epithelial cell proliferation and differentiation. It features a conserved N-terminal kinase domain with ATP-binding motif, a C-terminal serine-rich region, and structural motifs critical for substrate phosphorylation and enzyme activation. It localizes to the cytoplasm and nucleus of mouse intestinal crypt and villus epithelial cells, with negligible levels in non-intestinal tissues. The protein mediates Wnt signaling pathway modulation, with conserved motifs for binding to cytoskeletal and scaffolding proteins. Mouse ICK shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from other CDC2-like kinases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.