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Mouse Guanylate Cyclase 1 Beta 3 (GUCY1b3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Guanylate Cyclase 1 Beta 3 (GUCY1b3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GUCY1b3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The guanylate cyclase soluble subunit beta-1 facilitates responses to nitric oxide (NO) by catalyzing the production of the signaling molecule cGMP. In mice, the absence of GUCY1B1 results in intestinal dysmotility, leading to gastrointestinal dysfunction, which underscores its critical role in maintaining normal intestinal motility. In mouse tumor models, GUCY1B1 expression levels are closely linked to tumor progression. For instance, in mouse lung adenocarcinoma, decreased expression of GUCY1B1 is associated with increased tumor growth and resistance to chemotherapy. Research indicates that the loss of GUCY1B1 can significantly extend tumor growth duration, highlighting its role in tumor initiation and progression.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.