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Mouse Anti-Vancomycin (VM) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for vancomycin. It is purified by protein A. It can be applied to ELISA, WB, FIA and CLIA assays of vancomycin. The antigen for this antibody is VG8F163.
Specifications
Target Information
Vancomycin is a glycopeptide antibiotic that targets the terminal D-alanyl-D-alanine of the peptidoglycan precursors in bacterial cell walls. It binds to this site, preventing the cross-linking of peptidoglycan chains, which is essential for cell wall integrity. This inhibition leads to weakened cell walls and ultimately bacterial lysis. Vancomycin is particularly effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus species. Its unique mechanism of action makes it a crucial target for antibody development to enhance its therapeutic efficacy and overcome resistance mechanisms in treating serious bacterial infections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
