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Mouse Anti-Rat Beta-2-Microglobulin (b2M) Monoclonal Antibody

Cat. No.VD2N226

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for rat beta-2-microglobulin. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of rat beta-2-microglobulin.

Specifications

Application WB; IHC; ICC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone A19N38
Host Mouse
Target Species Rat
Species Reactivity Rat
Specificity Rat Beta-2-Microglobulin
Isotype IgG2
Immunogen Recombinant protein of rat beta-2-microglobulin
Purification Purified by Protein A and Protein G
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat Beta-2-Microglobulin (B2M) is a 12 kDa protein that forms a critical subunit of the major histocompatibility complex (MHC) class I molecules. It stabilizes the tertiary structure of the MHC class I α-chain, which is essential for presenting antigenic peptides to cytotoxic T lymphocytes. B2M is synthesized by all nucleated cells and is also a component of the neonatal Fc receptor, which regulates the turnover of albumin and IgG. Additionally, B2M is involved in iron metabolism through its interaction with the HFE protein, which controls hepcidin expression in the liver.

Target Rat Beta-2-Microglobulin
Target Synonym BMG; B2MG
Gene ID 24223
UniProt ID P07151

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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