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Rabbit Anti-Mouse Reticulocalbin 2 (RCN2) Polyclonal Antibody

Cat. No.VD2N830

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse reticulocalbin 2. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse reticulocalbin 2.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N329
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Reticulocalbin 2
Isotype IgG
Immunogen Recombinant protein of mouse reticulocalbin 2
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Reticulocalbin 2 (RCN2) is a calcium-binding protein predominantly localized in the endoplasmic reticulum (ER). It plays a crucial role in maintaining calcium homeostasis within the ER and is involved in the unfolded protein response (UPR) to alleviate ER stress. RCN2 helps regulate protein folding and quality control processes, ensuring proper cellular function. Its expression is induced under stress conditions, highlighting its importance in cellular adaptation and survival mechanisms. RCN2 is an important target for studying ER stress and related physiological processes in mouse models.

Target Mouse Reticulocalbin 2
Target Synonym E6BP; ERC-55; ERC55; Endoplasmic Reticulum Calcium-Binding Protein 55kD; E6-binding protein
Gene ID 26611
UniProt ID Q8BP92

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Li, Jing, et al. "Reticulocalbin 2 as a potential biomarker and therapeutic target for atherosclerosis." Cells 11.7 (2022): 1107.
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