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Mouse Anti-Gentamicin (GM) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for gentamicin. It is purified by protein A. It can be applied to ELISA, WB, FIA and CLIA assays of gentamicin. The antigen for this antibody is VG8F138.
Specifications
Target Information
Gentamicin is an aminoglycoside antibiotic that targets the 30S subunit of bacterial ribosomes. It binds to the 16S rRNA, disrupting protein synthesis by causing misreading of the mRNA code and inhibiting the release of the initiation complex. This leads to the production of nonfunctional proteins and ultimately bacterial cell death. Gentamicin is effective against a wide range of Gram-negative and some Gram-positive bacteria, including Escherichia coli and Pseudomonas aeruginosa. Its specific interaction with the ribosome makes it a valuable target for antibody development to enhance its therapeutic efficacy and specificity in treating bacterial infections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
