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Mouse Anti-Amanitin (AMA) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for amanitin. It can be applied to ELISA, WB, FIA and CLIA assays of amanitin.
Specifications
Target Information
Amanitin is a toxic compound found in certain mushrooms, particularly in the genus Amanita. It targets RNA polymerase II in eukaryotic cells, an enzyme essential for the transcription of DNA into mRNA. By binding to this enzyme, amanitin inhibits the synthesis of mRNA, leading to a halt in protein production and ultimately causing cell death. This mechanism underlies its severe toxicity in humans and animals. Its specific interaction with RNA polymerase II makes it a relevant target for antibody development to enhance detection and monitoring in toxicology and environmental studies, supporting the identification and management of poisonous mushrooms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.